HARE Growth Factor
Hair cortical cells
Ø The dermal papilla (DP) cells inside the hair follicles play a pivotal role in hair regeneration and growth.
Ø The DP cells control hair regeneration by secreting various cell proliferation proteins.
Ø The number of DP cells directly affect hair growth, shape, follicular formation and hair growth cycle.
Ø When the phase of hair growth cycle shifts from the anagen (growth) phase into the catagen (falling off) and telogen (resting) phase,the number of the DP cells rapidly decreases due to cell death.
Ø For an optimized hair regeneration, the supply of growth factor (which maintains the functions of DP cells) is vital.
Dermal papilla (DP) cells
DP cell activation in hair
Induce cell activation
80 ~ 90 %
2 ~ 3 %
10 ~ 15 %
Hair stem cell
cell growth factor
create hair fiber
Ø HARE Growth Factor protein binds specifically to the DP cells (highly safe).
Ø Stimulates DP cells to:
1. Prevent cell death and promote cell multiplication (prevents hair loss and promotes hair growth).
2. Promote multiplication of hair stem cells (hair regeneration).
3. Promote activation of keratinocytes for hair regeneration and melanocytes for hair pigmentation (promote cell activation).
HARE's ketinocyte activation in skin
Ø HARE Growth Factor protein also binds to the Keratinocyte.
Ø Stimulates Keratinocyte to:
1. Induce the proliferation and survival of keratinocyte for skin rejuvenation.
2. Enhance the differentiation of keratinocyte to corneocyte for skin rejuvenation.
3. Activate the keratin protein production for hair and nail regeneration.